卫生部


卫生部关于印发《狂犬病暴露预防处置工作规范（2009年版）》的通知


各省、自治区、直辖市卫生厅局，新疆生产建设兵团卫生局，中国疾病预防控制中心：

2006年10月，我部印发了《狂犬病暴露后处置工作规范（试行）》（卫办疾控发〔2006〕176号），对规范医疗卫生机构开展狂犬病暴露后处置工作起到了积极的促进作用。为适应我国狂犬病疫苗和被动免疫制剂研制技术的最新进展，指导各地进一步做好狂犬病暴露预防处置工作，降低狂犬病的发病率，保护人民群众身体健康，我部组织制定了《狂犬病暴露预防处置工作规范（2009年版）》，现予以印发。请各地结合工作实际，严格执行并切实做好医疗卫生机构专业人员的培训工作。本规范自印发之日起施行，《狂犬病暴露后处置工作规范（试行）》同时废止。

二〇〇九年十二月十一日

狂犬病暴露预防处置工作规范

（2009年版）

第一条 狂犬病暴露是指被狂犬、疑似狂犬或者不能确定健康的狂犬病宿主动物咬伤、抓伤、舔舐粘膜或者破损皮肤处，或者开放性伤口、粘膜接触可能感染狂犬病病毒的动物唾液或者组织。

第二条 按照接触方式和暴露程度将狂犬病暴露分为三级。

接触或者喂养动物，或者完好的皮肤被舔为I级。

裸露的皮肤被轻咬，或者无出血的轻微抓伤、擦伤为Ⅱ级。

单处或者多处贯穿性皮肤咬伤或者抓伤，或者破损皮肤被舔，或者开放性伤口、粘膜被污染为Ⅲ级。

第三条 狂犬病预防处置门诊的医师在判定暴露级别后，根据需要，要立即进行伤口处理；在告知暴露者狂犬病危害及应当采取的处置措施并获得知情同意后，采取相应处置措施。

第四条 判定为I级暴露者，无需进行处置。

第五条 判定为Ⅱ级暴露者，应当立即处理伤口并接种狂犬病疫苗。确认为Ⅱ级暴露者且免疫功能低下的，或者Ⅱ级暴露位于头面部且致伤动物不能确定健康时，按照Ⅲ级暴露处置。

第六条 判定为Ⅲ级暴露者，应当立即处理伤口并注射狂犬病被动免疫制剂，随后接种狂犬病疫苗。

第七条 伤口处理包括彻底冲洗和消毒处理。局部伤口处理越早越好，就诊时如伤口已结痂或者愈合则不主张进行伤口处理。清洗或者消毒时如果疼痛剧烈，可给予局部麻醉。

伤口冲洗：用20%的肥皂水（或者其他弱碱性清洁剂）和一定压力的流动清水交替彻底清洗、冲洗所有咬伤和抓伤处至少15分钟。然后用生理盐水（也可用清水代替）将伤口洗净，最后用无菌脱脂棉将伤口处残留液吸尽，避免在伤口处残留肥皂水或者清洁剂。较深伤口冲洗时，用注射器或者高压脉冲器械伸入伤口深部进行灌注清洗，做到全面彻底。

消毒处理：彻底冲洗后用2-3%碘酒（碘伏）或者75%酒精涂擦伤口。如伤口碎烂组织较多，应当首先予以清除。

第八条 如伤口情况允许，应当尽量避免缝合。伤口的缝合和抗生素的预防性使用应当在考虑暴露动物类型、伤口大小和位置以及暴露后时间间隔的基础上区别对待。

伤口轻微时，可不缝合，也可不包扎，可用透气性敷料覆盖创面。

伤口较大或者面部重伤影响面容或者功能时，确需缝合的，在完成清创消毒后，应当先用抗狂犬病血清或者狂犬病人免疫球蛋白作伤口周围的浸润注射，使抗体浸润到组织中，以中和病毒。数小时后（不少于2小时）再行缝合和包扎；伤口深而大者应当放置引流条，以利于伤口污染物及分泌物的排出。

伤口较深、污染严重者酌情进行抗破伤风处理和使用抗生素等，以控制狂犬病病毒以外的其他感染。

第九条 特殊部位的伤口处理。

眼部：波及眼内的伤口处理时，要用无菌生理盐水冲洗，一般不用任何消毒剂。

口腔：口腔的伤口处理最好在口腔专业医师协助下完成，冲洗时注意保持头低位，以免冲洗液流入咽喉部而造成窒息。

外生殖器或肛门部粘膜：伤口处理、冲洗方法同皮肤，注意冲洗方向应当向外，避免污染深部粘膜。

以上特殊部位伤口较大时建议采用一期缝合（在手术后或者创伤后的允许时间内立即缝合创口），以便功能恢复。

第十条 首次暴露后的狂犬病疫苗接种应当越早越好。

接种程序：一般咬伤者于0（注射当天）、3、7、14和28天各注射狂犬病疫苗1个剂量。狂犬病疫苗不分体重和年龄，每针次均接种1个剂量。

注射部位：上臂三角肌肌内注射。2岁以下婴幼儿可在大腿前外侧肌肉内注射。禁止臀部注射。

如不能确定暴露的狂犬病宿主动物的健康状况，对已暴露数月而一直未接种狂犬病疫苗者也应当按照接种程序接种疫苗。
第十一条 正在进行计划免疫接种的儿童可按照正常免疫程序接种狂犬病疫苗。接种狂犬病疫苗期间也可按照正常免疫程序接种其他疫苗，但优先接种狂犬病疫苗。

第十二条 接种狂犬病疫苗应当按时完成全程免疫，按照程序正确接种对机体产生抗狂犬病的免疫力非常关键，当某一针次出现延迟一天或者数天注射，其后续针次接种时间按延迟后的原免疫程序间隔时间相应顺延。

第十三条 应当尽量使用同一品牌狂犬病疫苗完成全程接种。若无法实现，使用不同品牌的合格狂犬病疫苗应当继续按原程序完成全程接种，原则上就诊者不得携带狂犬病疫苗至异地注射。

第十四条 狂犬病病死率达100%，暴露后狂犬病疫苗接种无禁忌症。接种后少数人可能出现局部红肿、硬结等，一般不需做特殊处理。极个别人的反应可能较重，应当及时就诊。发现接种者对正在使用的狂犬病疫苗有严重不良反应时，可更换另一种狂犬病疫苗继续原有程序。

第十五条 冻干狂犬病疫苗稀释液应当严格按照说明书要求使用。

第十六条 被动免疫制剂严格按照体重计算使用剂量，一次性足量注射。狂犬病人免疫球蛋白按照每公斤体重20个国际单位（20IU/kg），抗狂犬病血清按照每公斤体重40个国际单位（40IU/kg）计算。如计算剂量不足以浸润注射全部伤口，可用生理盐水将被动免疫制剂适当稀释到足够体积再进行浸润注射。

第十七条 注射部位如解剖学结构可行，应当按照计算剂量将被动免疫制剂全部浸润注射到伤口周围，所有伤口无论大小均应当进行浸润注射。当全部伤口进行浸润注射后尚有剩余被动免疫制剂时，应当将其注射到远离疫苗注射部位的肌肉。暴露部位位于头面部、上肢及胸部以上躯干时，剩余被动免疫制剂可注射在暴露部位同侧背部肌肉群（如斜方肌），狂犬病疫苗接种于对侧。暴露部位位于下肢及胸部以下躯干时，剩余被动免疫制剂可注射在暴露部位同侧大腿外侧肌群。

第十八条 如未能在接种狂犬病疫苗的当天使用被动免疫制剂，接种首针狂犬病疫苗7天内（含7天）仍可注射被动免疫制剂。不得把被动免疫制剂和狂犬病疫苗注射在同一部位；禁止用同一注射器注射狂犬病疫苗和被动免疫制剂。

第十九条 对于粘膜暴露者，应当将被动免疫制剂滴/涂在粘膜上。如果解剖学结构允许，也可进行局部浸润注射。剩余被动免疫制剂参照前述方法进行肌肉注射。

第二十条 注射抗狂犬病血清前必须严格按照产品说明书进行过敏试验。

第二十一条 再次暴露后处置。

伤口处理：任何一次暴露后均应当首先、及时、彻底地进行伤口处理。

疫苗接种：一般情况下，全程接种狂犬病疫苗后体内抗体水平可维持至少1年。如再次暴露发生在免疫接种过程中，则继续按照原有程序完成全程接种，不需加大剂量；全程免疫后半年内再次暴露者一般不需要再次免疫；全程免疫后半年到1年内再次暴露者，应当于0和3天各接种1剂疫苗；在1-3年内再次暴露者，应于0、3、7天各接种1剂疫苗；超过3年者应当全程接种疫苗。

被动免疫制剂注射：按暴露前（后）程序完成了全程接种狂犬病疫苗（细胞培养疫苗）者，不再需要使用被动免疫制剂。


第二十二条 使用合格的、正规途径获得的疫苗全程免疫后，一般情况下无需对免疫效果进行检测。如需检测抗体水平，应当采取中和抗体试验进行检测，包括快速荧光灶抑制试验（RFFIT）、小鼠脑内中和试验2种方法。

第二十三条 不良反应处理参照《预防接种工作规范》（卫疾控发〔2005〕373号）进行。

第二十四条 狂犬病高暴露风险者应当进行暴露前免疫，包括从事狂犬病研究的实验室工作人员、接触狂犬病病人的人员、兽医等。

第二十五条 暴露前基础免疫程序为0、7、21（或28）天各接种1剂量狂犬病疫苗。持续暴露于狂犬病风险者，全程完成暴露前基础免疫后，在没有动物致伤的情况下，1年后加强1针次，以后每隔3-5年加强1针次。

第二十六条 对妊娠妇女、患急性发热性疾病、过敏性体质、使用类固醇和免疫抑制剂者可酌情推迟暴露前免疫。免疫缺陷病人不建议暴露前免疫，如处在高暴露风险中，亦可进行暴露前免疫，但完成免疫接种程序后需进行中和抗体检测。对一种疫苗过敏者，可更换另一种疫苗继续原有程序。

第二十七条 县级以上地方卫生行政部门应当对辖区内狂犬病暴露预防处置门诊进行合理布局。从事狂犬病暴露预防处置的医师须经县级以上地方卫生行政部门培训考核合格后，方可上岗。

第二十八条 狂犬病暴露预防处置门诊应当具备必要的伤口冲洗、冷链等设备和应急抢救药品。

第二十九条 狂犬病暴露预防处置门诊应当建立健全相应的管理制度。主要包括冷链管理、知情同意书、接种登记、不良反应登记报告等。

第三十条 如药典或者产品说明书的内容发生变更，本规范的相关内容从其规定。


附件：狂犬病疫苗和抗狂犬病血清/狂犬病人免疫球蛋白使用知情同意书
http://images.china.cn/attachement/jpg/site1000/20091217/001ec949f8550c93d43302.jpg

中国保险监督管理委员会


中华人民共和国外资保险公司管理条例实施细则(英文版)


Detailed Rules for Implementation of Regulations of the People’s Republic of China on Administration of Foreign-funded Insurance Companies

Article 1
These Rules are formulated in accordance with the Insurance Law of the People’s Republic of China and the Regulations of the People’s Republic of China on Administration of Foreign-funded Insurance Companies (hereinafter referred to as “the Regulations”).

Article 2
A foreign insurance company under the Regulations refers to an insurance company registered and conducting insurance business outside the territory of China.

Article 3
The proportion of foreign equity in an insurance company incorporated within the territory of China by a foreign insurance company with a Chinese company or enterprise that conducts life insurance business (hereinafter referred to as “joint-equity life insurance company”) shall be no more than 50% of the total equity of the company.

The shares of a joint-equity life insurance company directly or indirectly held by a foreign insurance company shall not exceed the limit of proportion as stipulated in the preceding paragraph.

Article 4
For a foreign-funded insurance company established within the territory of China before the Regulations became effective with registered capital or working capital of less than RMB 200 million or an equivalent amount in a freely convertible currency, its registered capital or working capital shall be fully paid within 2 years after these Rules become effective. For those who fail to fully pay the registered capital or working capital, China Insurance Regulatory Commission shall not grant approval to their application for operation of new business.

Article 5
The registered capital or working capital of a foreign-funded insurance company shall be the actually paid-up currency.

Article 6
After establishing a branch, the foreign insurance company shall not withdraw the working capital in any form.

Article 7
The period of operation of insurance business being more than 30 years, which is mentioned in Item 1 of Article 8 of the Regulations, means that the foreign insurance company shall have continuously been running insurance business for more than 30 years, and the foreign insurance company’s acquisition of another institution or merger with another institution to establish a new insurance company, shall not affect the calculation of the business operation period.

The business operation period of a subsidiary of a foreign insurance company shall start from the date of establishment of the subsidiary.

Article 8
The representative office mentioned in Item 2 of Article 8 of the Regulations refers to the following representative offices approved by China Insurance Regulatory Commission (hereinafter referred to as “CIRC”):

(1) The representative office established by a foreign insurance company;
(2) The representative office established by a group to which a foreign insurance company belongs.

Article 9
The representative office established by a foreign insurance company or its group to which the insurance company belongs is only applicable to application for establishing one foreign-funded insurance company.

Article 10
The end of the year prior to the application for the establishment mentioned in Item 3 of Article 8 of the Regulations refers to the end of the previous fiscal year before the date of application.

Article 11
The other prudential requirements mentioned in Item 7 of Article 8 of the Regulations shall at least include the following requirements:

(1) Reasonable structure for corporate governance;
(2) Stable and sound risk control system;
(3) Sound internal control system;
(4) Effective Management Information System;
(5) Good operating performance without records of serious violation of laws and regulations.

Article 12
Where the applicant fails to provide the business license (duplicate) as stipulated in Item 2 of Article 9 of the Regulations, the applicant may provide a valid copy of the business license or a written certificate issued by the relevant authority evidencing the applicant’s eligibility to conduct insurance business.

Article 13
The certificate mentioned in Item 2 of Article 9 of the Regulations, which is issued by the relevant authority of the country or region where the foreign applicant is located to evidence the applicant’s solvency, shall include one of the following contents:

(1) Certifying that the applicant complies with the regulatory requirements of the country or region on solvency in the previous fiscal year as of the date when the relevant authority issues the certificate;
(2) Certifying that the applicant has no record of incompliance with the standard of the country or region on solvency in the previous fiscal year as of the date when the relevant authority issues the certificate.

Article 14
The Letter of Comments issued by the relevant authority of the country or region where the foreign applicant is located concerning the applicant’s application, which is mentioned in Item 2 of Article 9 of the Regulations, shall include the following contents:

(1) Whether the application for the establishment of an insurance institution in China complies with the laws and rules of the applicant’s country or region;
(2) Whether the authority approves the applicant’s application;
(3) The record of the punishment imposed on the applicant in the last three years prior to the date of issuance of the Letter of Comments by the relevant authority;

Article 15
The annual report mentioned in Item 3 of Article 9 of the Regulations shall include the Balance Sheets, Statements of Profit and Loss, and Cash Flow Statements of the applicant in the last three fiscal years prior to the date of application.

The annual report mentioned in the preceding paragraph shall be attached with the auditor’s report issued by an accounting or auditing firm authorized by the country or region where the applicant is located.

Article 16
Except otherwise specified by the laws or administrative regulations or approved by the State Council, the Chinese applicant mentioned in Item 4 of Article 9 of the Regulations shall satisfy the following requirements:

(1) The companies or enterprises with the capacity of legal person registered at the administration department of industry and commerce, excluding commercial banks, securities organizations and the foreign-funded enterprises specified in the Law of the People’s Republic of China on Foreign-funded Enterprises;
(2) Being approved by the administrative authority of the enterprise or its shareholders’ meeting;
(3) Good operating performance and in the previous fiscal year as of the application date being profitable;
(4) Making the investment with self-owned capital from legitimate sources.

Article 17
The relevant documents to be submitted by a Chinese applicant for the establishment of a joint-equity insurance company shall include business license (duplicate), articles of association, business structure, operation history, annual report and punishment record for the last three years.

Article 18
The person in charge of the preparation of a foreign-funded insurance company shall satisfy the following requirements:

(1) Academic degree above junior college level;
(2) Insurance or related work experience for over 2 years;
(3) No illegal and criminal record.

Article 19
Where an applicant applies for the extension of the preparation period according to the provisions specified in Article 11 of the Regulations, he shall, within 1 month before expiration of the original preparation period, submit a written application to CIRC and explain the reason.

Article 20
The preparation report mentioned in Item 1 of Article 11 of the Regulations shall summarize all the issues stated in other paragraphs under this article.

Article 21
The statutory capital verification organization mentioned in Item 4 of Article 11 of the Regulations refers to an accounting firm complying with the requirements of CIRC.

Article 22
The capital verification certificate mentioned in Item 4 of Article 11 of the Regulations shall include the following contents:

(1) A Capital Verification Report issued by a statutory capital verification organization;
(2) A copy of the original bank receipt voucher evidencing payment of the registered capital or working capital.

Article 23
The main person-in-charge mentioned in Item 5 of Article 11 of the Regulations refers to the general manager of the proposed branch of a foreign insurance company.

The letter of attorney issued to the person to be appointed as the main person-in-charge of the proposed branch of the foreign insurance company, refers to the letter of attorney issued to the person to be appointed as the general manager of the proposed branch of the foreign insurance company, which is signed by the Chairman of the Board of Directors or General Manager of the foreign insurance company.

The letter of attorney shall explicitly specify the scope of authorization granted to the authorized person.

Article 24
The senior managerial personnel of the proposed company mentioned in Item 6 of Article 11 of the Regulations shall have the qualifications specified by CIRC.

The senior managerial personnel of the branch of a foreign insurance company shall have the qualifications equal to those required for the counterparts in the headquarters of an insurance company.

Article 25
The materials regarding business place of the proposed company mentioned in Item 9 of Article 11 of the Regulations refers to the supporting documents evidencing the ownership or use-right of the business place.

The materials concerning other facilities related to the business mentioned in Item 9 of Article 11 of the Regulations shall include at least information about configuration of computer facilities, network construction and information management system.

Article 26
The following documents or materials to be provided by a foreign insurance company for an application for the establishment of a foreign-funded insurance company according to the requirements specified in the Regulations and these Rules, shall be notarized by a public notary legally established in the local country or region, or verified by the embassy or consulate of China in that country:

(1) The business license (duplicate) or valid copy of the business license;
(2) A letter of attorney issued to the proposed person-in-charge of the branch of a foreign insurance company;
(3) A letter of guarantee of a foreign insurance company to undertake the obligations of tax and duties payment and debts repayment on behalf of its branch in China.

Article 27
A foreign-funded insurance company may apply for establishing branches as needed according to business development.

The branch of a foreign insurance company can only conduct business within the territory of the province, autonomous region or municipality where the branch is located. Where the joint-equity insurance company or wholly-owned insurance company is prepared to conduct business in any other province, autonomous region or municipality outside its locality, it shall establish a branch in the place concerned.

A foreign insurance company may, according to actual circumstances, apply for establishing a central sub-branch or sub-branch, operating office or marketing service office. The establishment and management of marketing service offices shall be subject to other applicable regulations of CIRC, if any.

Article 28
Where a joint-equity or wholly-owned insurance company which has been established with a minimum registered capital of RMB200 million, applies for the first time for the establishment of a branch in every other province, autonomous region, or municipality outside its locality, it shall increase the registered capital by no less than RMB20 million.

By the time of applying for the establishment of a branch, if the registered capital of a joint-equity or wholly-owned insurance company has reached the amount as stipulated in the preceding paragraph, the company will no longer be required to increase its registered capital.

Where the registered capital of a joint-equity or wholly-owned insurance company has reached RMB500 million and where the solvency of the company is adequate, no increase of registered capital is required when the company applies for the establishment of a branch.

Article 29
A foreign-funded insurance company that applies for the establishment of a branch shall satisfy the following requirements:

(1) Its solvency margin shall comply with relevant regulations specified by CIRC.
(2) Its internal control system is sound and there is no record of punishment; where the operating period exceeds 2 years, there is no record of punishment in the most recent 2 years;
(3) It has senior managerial personnel of the branch with the relevant qualifications specified by CIRC.

Article 30
A foreign-funded insurance company that applies for the establishment of a branch shall submit an application to CIRC and provide the following documents in triplicate:

(1) A letter of application for establishment;
(2) Audited solvency status reports as of the end of the previous fiscal year and as of the end of the last quarter;
(3) A three-year business development plan and market analysis for the proposed branch;
(4) Resume(s) of the person(s)-in-charge of the organization preparation and relevant certificates.

Article 31
CIRC shall examine the application and decide, within 20 days after receiving the complete application documents, whether or not to grant approval; in case no approval is granted, CIRC shall inform the applicant in writing of the decision and explain the reason.

After approval is granted, the applicant shall complete the preparation within 6 months. Where the applicant fails to do so within the prescribed time limit, if the reason is justified and subject to approval by CIRC, the period may be extended for 3 months. Where the preparation is still not completed within the extended period, the original approval document issued by CIRC becomes void automatically.

The preparing body may not be engaged in any commercial activities concerning insurance.

Article 32
After the preparation is completed, the applicant shall apply to CIRC for opening business and submit the following documents in triplicate:

(1) A letter of application for opening business;
(2) A progress report of the preparation work;
(3) Resume(s) of senior managerial personnel to be appointed and relevant certificates;
(4) Relevant certificates of ownership or use-right of the office for the proposed branch, information regarding the configuration of computer facilities, network construction, and internal structure and staff.

Article 33
CIRC shall decide, within 20 days after receiving the complete application documents for opening business, whether or not to grant approval; in case the application is approved, a license for conducting insurance business shall be issued to the branch; in case the application is disapproved, CIRC shall inform the applicant in writing of the decision and explain the reason.

The branch with approval for opening business shall go through the formalities of business registration at the administration department of industry and commerce by presenting the approval document and the license for conducting insurance business and accordingly obtain business license from the authority before opening business.

Article 34
Unless otherwise stipulated in these Rules, the examination and administration of the qualifications of the senior managerial personnel of a foreign-funded insurance company and its branches shall be subject to the relevant regulations of CIRC.

Article 35
Where a joint-equity or wholly-owned property insurance company applies for dissolution when it splits, or merges with another one, or dissolves pursuant to the articles of association, such dissolution must be subject to approval of CIRC and the following documents shall be submitted:

(1) A letter of application signed by the Chairman of the Board of Directors of the company;
(2) The resolution of the meeting of shareholders;
(3) Composition of the proposed liquidation group and a plan for liquidation;
(4) A proposal for solving the outstanding liabilities.

Article 36
The joint-equity or wholly-owned property insurance company whose dissolution has been approved by CIRC shall, from the date of receiving the approval document from CIRC, terminate any new business activities and hand in the license for conducting insurance business to CIRC and form a liquidation group within 15 days.

Article 37
The liquidation group shall, within 5 days after its establishment, inform the relevant authorities concerning the administration departments of industry and commerce, tax, labor and social security in writing of the liquidation procedure and conditions.

Article 38
The liquidation group shall, within 1 month from the date of establishment, appoint an accounting firm pursuant to the requirements of CIRC to conduct auditing, and shall deliver an auditor’s report to CIRC within three months from the date of appointment.

Article 39
The liquidation group shall submit the latest liability liquidation and assets disposal report to CIRC before the tenth date of each month.

Article 40
The newspaper mentioned in Article 28 of the Regulations refers to the newspaper specified by CIRC.

Article 41
The foreign property insurance company that applies for cancellation of its branch in China shall submit an application to CIRC for approval and present the following materials:

(1) A letter of application signed by the Board of Directors or General Manager of the foreign property insurance company;
(2) Composition of the proposed liquidation group and a plan for liquidation;
(3) A proposal for solving the outstanding liabilities.

The procedures of application for dissolution of a joint-equity or foreign-funded property insurance company specified in the Regulations and these Rules shall be applicable to the specific procedures for the foreign property insurance company to cancel its branch in China.

Where the head office of a branch of a foreign property insurance company is dissolved or cancelled or declared bankruptcy according to law, the liquidation and liability disposal of the branch of such foreign property insurance company shall comply with the regulations concerning dissolution of the joint-equity or wholly-owned property insurance company stipulated in Article 30 of the Regulations and these Rules.

Article 42
The foreign-funded insurance company in violation of the relevant provisions of these Rules shall be subject to punishment by CIRC according to the provisions specified in Insurance Law, the Regulations and other relevant laws and regulations.

Article 43
The documents, materials and written reports to be submitted or reported under the Regulations and these Rules shall be prepared in Chinese version, and the Chinese version shall prevail in the event of discrepancy between the Chinese version and the foreign language version.

Article 44
The period specified in the Regulations and these Rules shall start from the date when the relevant materials are delivered to CIRC. If the application documents provided by the applicant is incomplete and further delivery is needed, the period shall start from the date when the supplementary materials are delivered to CIRC.

The period concerning approval and report delivery prescribed in these Rules refers to working days.

Article 45
The issues concerning administration of a foreign-funded insurance company that are not specified in the Regulations or these Rules shall be governed by the applicable laws, administrative rules and relevant regulations of CIRC.

The establishment of a foreign-funded reinsurance company shall comply with the Regulations on Establishment of Reinsurance Companies. The issues not specified in the Regulations on Establishment of Reinsurance Companies shall be governed by these Rules.

Article 46
These Rules shall, mutatis mutandis, apply to insurance companies that are established and operated in Chinese mainland by insurance companies from Hong Kong Special Administrative Region, Macao Special Administrative Region or Taiwan region. The issues otherwise stipulated in the laws, administrative rules or administrative protocols shall be governed by the stipulations therein.

Article 47
These Rules shall come into effect as of June 15, 2004.